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Korlym Side Effects

While clinical studies have shown that many people taking Korlym tolerate the medicine well, let your healthcare provider know right away if you develop unusual tiredness, unexplained weight gain, or other potentially serious reactions while taking this medication. Studies have shown that some of the most commonly reported problems include nausea, fatigue, and headaches.

An Introduction to Korlym Side Effects

Just like any medicine, Korlym™ (mifepristone) can cause side effects. However, not everyone who takes the drug will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Korlym. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects of Korlym

Korlym has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking the drug were carefully documented. As it result, it was possible to see what side effects occurred and how often they appeared.
In these studies, the most common Korlym side effects included the following:
  • Nausea -- in up to 48 percent of people
  • Fatigue -- up to 48 percent
  • Headache -- up to 44 percent
  • Overgrowth of the lining of the uterus (endometrial hypertrophy) -- up to 38 percent
  • Low blood potassium levels -- up to 34 percent
  • Joint pain -- up to 30 percent
  • Vomiting -- up to 26 percent
  • Swelling of the arms, hands, legs, ankles, or feet -- up to 26 percent
  • High blood pressure (hypertension) -- up to 24 percent
  • Dizziness -- up to 22 percent
  • Decreased appetite -- up to 20 percent.
Other reactions, occurring in 5 percent to 18 percent of people, included:
  • Dry mouth
  • Back pain
  • Muscle pain
  • Arm and leg pain
  • General pain
  • Shortness of breath
  • Symptoms of the common cold, such as nasal congestion
  • Diarrhea
  • Constipation
  • Drowsiness
  • Abnormal vaginal bleeding
  • Anxiety
  • Abdominal (stomach) pain
  • Heartburn or indigestion
  • Thirst
  • Weakness or lack of energy
  • General feelings of discomfort or illness
  • Insomnia.
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Korlym Drug Information

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