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Janumet Drug Interactions

Janumet Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Janumet is combined with any of the drugs listed above.
 
Certain Decongestants
Taking Janumet with certain decongestants can make Janumet less effective, potentially increasing your chance of high blood sugar (hyperglycemia). Decongestants are in many cough and cold products, so be sure to talk to your healthcare provider before taking any cough or cold medications during treatment with Janumet.
 
Calcium Channel Blockers
Combining Janumet with calcium channel blockers can make Janumet less effective, which may increase your risk of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your Janumet dose, especially when starting or stopping a calcium channel blocker.
 
However, taking Janumet with nifedipine (a calcium channel blocker) can also increase the level of Janumet in your blood. Your healthcare provider may need to adjust your dose of Janumet in this situation to prevent interactions from occurring.
 
Cimetidine
Taking Janumet with cimetidine can increase the level of Janumet in your blood, possibly increasing your risk of side effects. Your healthcare provider may need to adjust your dose of these medications or suggest an alternative to cimetidine, depending on your particular situation.
 
Corticosteroids
If Janumet is taken with corticosteroids, it can make Janumet less effective, increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your Janumet dose, especially when starting or stopping a corticosteroid.
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