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Side Effects of Insulin Lispro

Potential side effects of insulin lispro include low blood sugar levels, a skin reaction at the injection site, or skin thickening or pitting at injection site. While most side effects are mild, some are potentially serious and require immediate medical attention. These insulin lispro side effects include signs of an allergic reaction and symptoms of low blood sugar (such as cold sweats or seizures).

An Introduction to Side Effects of Insulin Lispro

As with any medicine, side effects can occur with insulin lispro (Humalog®). However, not everyone who takes the drug will experience side effects. In fact, many people tolerate it well. If insulin lispro side effects do occur, they are often minor and either require no treatment or can be treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with insulin lispro. Your healthcare provider can discuss a more complete list of insulin lispro side effects with you.)

Serious Insulin Lispro Side Effects: Warning Signs

Some side effects with insulin lispro are potentially serious and should be reported immediately to your healthcare provider. Some of the warning signs of these serious side effects include:
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Swelling of the mouth or throat
    • Wheezing or other difficulty breathing
  • Symptoms of low blood sugar, such as:
    • Changes in behavior, such as irritability or mood swings
    • Loss of coordination
    • Difficulty speaking
    • Sweating
    • Dizziness
    • Cold sweats
    • Shakiness
    • Extreme hunger
    • Blurry vision
    • Confusion
    • Seizures
    • Unconsciousness.
Make sure people around you know how to recognize your particular signs of low blood sugar, since you may be too confused (due to low blood sugar) to recognize and adequately respond. Different people can have different signs of low blood sugar.
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Insulin Lispro Drug Information

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