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Insulin Glargine Dosage

Your healthcare provider will consider several factors when determining the best insulin glargine dosage for you. These factors include how you respond to insulin glargine, other medications you are taking, and other medical conditions you have. Insulin glargine comes in the form of an injection that is typically taken once a day. Your insulin glargine dose can be injected into the stomach, upper arm, or thigh.

Insulin Glargine Dosage: An Introduction

The dose of insulin glargine (Lantus®) your healthcare provider recommends will vary, depending on a number of factors, including:
  • Your current dose of other insulins
  • How you respond to insulin glargine (especially as measured by your blood sugar levels)
  • Other medications you are taking, including other diabetes medications
  • Other medical conditions you may have.
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.

What Is a "Unit" of Insulin Glargine?

In order to understand the dosing of insulin glargine and other insulin medications, it is important to understand what exactly a "unit" of insulin is. There are different types of insulin; however, a single unit of insulin should have the same biological activity, no matter what type of insulin you use, as all insulins are compared to a single standard.

Insulin Glargine Dosing Guidelines

Insulin glargine is taken once daily. Although it does not matter when you take the medication, you should take it consistently at the same time each day.
If you are using insulin glargine to replace another long-acting (once- or twice-daily) insulin, a unit-for-unit dose conversion will usually work fine. In other words, if you currently take 20 units of a long-acting insulin per day, your insulin glargine dosage would be 20 units once daily or 10 units twice daily. In some cases, such as when switching from a twice-daily insulin to insulin glargine, a slightly lower insulin glargine dose may be recommended. Some dose adjustment may be necessary, based on how you react to the medication.
For people with type 2 diabetes, if you are not currently using any insulin, insulin glargine is usually started at 10 units once daily.
Your healthcare provider will use your response to the starting insulin glargine dosage (as measured by your blood sugar levels) to recommend any dose changes.
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