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Drug Interactions With Inhaled Insulin

Monoamine Oxidase Inhibitors
Taking inhaled insulin with monoamine oxidase inhibitors can increase your risk of low blood sugar (hypoglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your inhaled insulin dose, especially when starting or stopping an MAOI.
 
Oral Contraceptives
If inhaled insulin is taken with oral contraceptives (birth control pills), this can make inhaled insulin less effective, potentially increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your inhaled insulin dose, especially when starting or stopping a birth control pill.
 
Phenothiazines
Taking inhaled insulin with phenothiazines can make inhaled insulin less effective, possibly increasing your chance of high blood sugar (hyperglycemia). To prevent this, you may need to be monitored more closely, and your healthcare provider may need to adjust your inhaled insulin dose, especially when starting or stopping a phenothiazine.
 
Oral Diabetes Medications
Combining inhaled insulin with oral diabetes drugs can increase your risk of low blood sugar (hypoglycemia). As a result, you may need to be monitored more closely, and your healthcare provider may need to adjust your inhaled insulin dose, especially when stopping or starting an oral diabetes medication.
 
Pentamidine
Taking inhaled insulin with pentamidine can increase your risk of low blood sugar (hypoglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your inhaled insulin dose, especially when stopping or starting pentamidine.
 
Pentoxifylline
If inhaled insulin is taken with pentoxifylline, it can increase your risk of low blood sugar (hypoglycemia). Depending on your situation, you may need to be monitored more closely, and your healthcare provider may need to adjust your inhaled insulin dose, especially when stopping or starting pentoxifylline.
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