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Drug Interactions With Inhaled Insulin

Certain Decongestants
If inhaled insulin and certain decongestants are combined, this can make inhaled insulin less effective, potentially increasing your chance of high blood sugar (hyperglycemia). Depending on your particular situation, you may need to be monitored more closely, and your healthcare provider may need to adjust your inhaled insulin dose, especially when starting or stopping a decongestant.
 
Clonidine
Taking inhaled insulin with clonidine can increase or decrease your blood sugar levels. To prevent this, you may need to be monitored more closely, and your healthcare provider may need to adjust your inhaled insulin dose, especially when starting or stopping clonidine. Clonidine can also mask the symptoms of hypoglycemia, which may prevent you from feeling when your blood sugar drops too low.
 
Corticosteroids
Combining inhaled insulin with corticosteroids can make inhaled insulin less effective, possibly increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your inhaled insulin dose, especially when starting or stopping a corticosteroid.
 
Danazol
If inhaled insulin is combined with danazol, this can make inhaled insulin less effective, possibly increasing your chance of high blood sugar (hyperglycemia). To prevent this interaction from occurring, you may need to be monitored more closely, and your healthcare provider may need to adjust your inhaled insulin dose, especially when starting or stopping danazol.
 
Diuretics
If inhaled insulin and diuretics are combined, this can make inhaled insulin less effective, increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your inhaled insulin dose, especially when starting or stopping a diuretic.
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