Glyburide and Metformin
Glyburide and Metformin EffectsThere have been several studies looking at the effects of glyburide and metformin for type 2 diabetes.
Glyburide and Metformin and Hemoglobin A1c
Hemoglobin A1c (HbA1c) is a test used to measure long-term blood sugar control. For people without diabetes, HbA1c results are usually less than 6 percent. People with diabetes usually have higher results. In one study, people taking glyburide and metformin lowered their HbA1c by up to 1.53 percent on average. In the same study, people taking glyburide or metformin alone did not decrease their HbA1c levels as much as people taking glyburide and metformin.
Studies have shown that the higher the HbA1c, the greater the chance of developing long-term problems related to diabetes. These problems include heart disease, diabetic retinopathy, diabetic neuropathy, and diabetic nephropathy. By getting blood sugar levels under control with glyburide and metformin, it may be possible to decrease the chances of developing these diabetes complications.
Glyburide and Metformin and Fasting Blood Sugar
Fasting blood sugar is another way to study the effects of diabetes drugs. In previous studies, people taking glyburide and metformin decreased their fasting blood sugar levels by 41.5 mg/dL on average. People taking glyburide or metformin alone did not decrease their fasting blood sugar levels as much as people taking glyburide and metformin.
When and How to Take Glyburide and MetforminSome general considerations for when and how to take glyburide and metformin include:
- Glyburide and metformin comes in tablet form. It should be taken by mouth once or twice daily with meals.
In order to prevent an upset stomach, it is best to take glyburide and metformin with food.
- Glyburide and metformin should be taken at the same time(s) each day to maintain an even level of the drug in your blood.
- For glyburide and metformin to work properly, it must be taken as prescribed. Glyburide and metformin will not work if you stop taking it.