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Generic Glyburide and Metformin

Various companies make a generic version of glyburide and metformin, including Sandoz and Teva Pharmaceuticals. The FDA has given an "AB" rating to these generic medications, which means they are considered equivalent to brand-name glyburide and metformin. However, these drugs may contain different inactive ingredients that could cause problems for certain people.

Generic Glyburide and Metformin: An Overview

Glyburide and metformin (Glucovance®) is a prescription medication that has been licensed as a type 2 diabetes treatment. It is a combination medication containing glyburide (DiaBeta®, Glynase®, or Micronase®) and metformin hydrochloride (Fortamet®, Glucophage®, Glucophage XR®, Glumetza®, or Riomet®).
Brand-name Glucovance is manufactured by Bristol-Myers Squibb Company. However, it is also available in generic form.

Strengths of Generic Glyburide and Metformin

Generic glyburide and metformin is available in the following strengths:
  • Glyburide and metformin 1.25 mg/250 mg tablets -- containing 1.25 mg glyburide and 250 mg metformin
  • Glyburide and metformin 2.5 mg/500 mg tablets -- containing 2.5 mg glyburide and 500 mg metformin
  • Glyburide and metformin 5 mg/500 mg tablets -- containing 5 mg glyburide and 500 mg metformin.


Who Makes Generic Glyburide and Metformin?

Various generic manufacturers make this medication, such as:
  • Actavis, U.S.
  • Par Pharmaceutical
  • Sandoz
  • Teva Pharmaceuticals.

Is Generic Glyburide and Metformin as Good as Glucovance?

All generic medications must have certain tests to compare them to brand-name medications. The U.S. Food and Drug Administration (FDA) then looks at these tests to decide if the generics are equivalent to the brand-name medications and assigns a rating to each one.
An "AB" rating means that the FDA has determined that a generic medication is equivalent to a brand-name medication. All of the generic glyburide and metformin versions currently available have an "AB" rating, which means they should be equivalent to Glucovance.
However, generic medications are allowed to have different inactive ingredients than the brand-name medication. This might include fillers, dyes, or other ingredients that may cause problems for people with allergies or sensitivities.
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