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Drug Interactions With Glyburide and Metformin

Isoniazid
Taking glyburide and metformin with isoniazid can make glyburide and metformin less effective, increasing your chance of high blood sugar (hyperglycemia). If you are taking glyburide and metformin with isoniazid, you may need to be monitored more closely, and your healthcare provider may need to adjust your glyburide and metformin dose -- especially when you are starting or stopping isoniazid.
 
Monoamine Oxidase Inhibitors (MAOIs)
Taking glyburide and metformin with monoamine oxidase inhibitors can increase your risk of low blood sugar (hypoglycemia). If you are taking these drugs together, you may need to be monitored more closely, and your healthcare provider may need to adjust your glyburide and metformin dose -- especially when you are starting or stopping an MAOI.
 
Niacin (Nicotinic Acid, Niaspan, Niacor, Nicolar)
Taking glyburide and metformin with niacin can make glyburide and metformin less effective, increasing your chance of high blood sugar (hyperglycemia). If you are taking glyburide and metformin with niacin, you may need to be monitored more closely, and your healthcare provider may need to adjust your glyburide and metformin dose -- especially when you are starting or stopping niacin.
 
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Taking glyburide and metformin with an NSAID can increase your risk of low blood sugar (hypoglycemia). If you are taking glyburide and metformin with an NSAID, you may need to be monitored more closely, and your healthcare provider may need to adjust your glyburide and metformin dose -- especially when you are stopping or starting an NSAID.
 
Oral Contraceptives
Taking glyburide and metformin with oral contraceptives (birth control pills) can make glyburide and metformin less effective, increasing your chance of high blood sugar (hyperglycemia). If you are taking glyburide and metformin with an oral contraceptive, you may need to be monitored more closely, and your healthcare provider may need to adjust your glyburide and metformin dose -- especially when you are starting or stopping an oral contraceptive.
7 Signs of High Blood Sugar

Glyburide and Metformin Info

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