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Drug Interactions With Glucotrol

Oral Contraceptives
If Glucotrol is taken with oral contraceptives (birth control pills), this can make Glucotrol less effective, increasing your chance of high blood sugar (hyperglycemia). As a result, you may need to be monitored more closely, and your healthcare provider may need to adjust your Glucotrol dose, especially when starting or stopping an oral contraceptive.
 
Phenothiazines
Taking Glucotrol with phenothiazines can make Glucotrol less effective, potentially increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your Glucotrol dose, especially when starting or stopping a phenothiazine.
 
Phenytoin
Combining Glucotrol with phenytoin can make Glucotrol less effective, which may increase your chance of high blood sugar (hyperglycemia). To prevent this, you may need to be monitored more closely, and your healthcare provider may need to adjust your Glucotrol dose, especially when starting or stopping phenytoin.
 
Probenecid
If Glucotrol is combined with probenecid, this can increase your risk of low blood sugar (hypoglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your Glucotrol dose, especially when starting or stopping probenecid, depending on your particular situation.
 
Salicylates
Taking Glucotrol with salicylates can increase your risk of low blood sugar (hypoglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your Glucotrol dose in these cases, especially when starting or stopping a salicylate.
 
Sulfonamides
If Glucotrol and sulfonamides are taken together, this can increase your risk of low blood sugar (hypoglycemia). As a result, you may need to be monitored more closely, and your healthcare provider may need to adjust your Glucotrol dose, especially when starting or stopping a sulfonamide.
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