Glucophage (Cont.)

Glucophage Effects

There have been several studies documenting the effects of Glucophage for type 2 diabetes. In these studies, Glucophage has been shown to decrease fasting blood sugar and to decrease hemoglobin A1c (HbA1c). HbA1c is a test used to measure long-term blood sugar control in people with diabetes. Normal HbA1c levels are usually less than 6 percent in people without diabetes; people with diabetes usually have higher HbA1c results.
 
Studies have shown that the higher the HbA1c, the greater the chance for developing long-term problems related to diabetes. This includes such problems as heart disease, diabetic retinopathy, diabetic neuropathy, and diabetic nephropathy. By getting blood sugar levels under control with Glucophage, it may be possible to decrease the chances for developing these diabetes complications.
 
Some studies also suggest that Glucophage may lead to weight loss (see Glucophage and Weight Loss).
 
(Click Benefits of Metformin for more specific information on the beneficial effects of Glucophage.)
 

When and How to Take Glucophage

Some general considerations for when and how to take Glucophage include:
 
  • Glucophage comes in tablet form. It should be taken by mouth, usually one to three times daily. The long-acting form, Glucophage XR, should be taken once daily with your evening meal.
     
  • Glucophage should be taken with food to reduce stomach upset.
     
  • The long-acting form (Glucophage XR) should be swallowed whole and should not be broken or crushed.
     
  • Glucophage should be taken at the same time(s) each day to maintain an even level of the drug in your blood.
     
  • For Glucophage to work properly, it must be taken as prescribed. Glucophage will not work if you stop taking it.
     
(Glucophage Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;