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Glucophage Dosage

Glucophage Dosing With Insulin

The starting dose of both Glucophage and Glucophage XR for people taking insulin is 500 mg once daily. The maximum total daily dose for people taking insulin is 2500 mg for Glucophage and 2000 mg for Glucophage XR. Usually, when adding Glucophage to insulin, you should continue with your normal insulin dose.
 

General Glucophage Dosing Information

Some considerations for people taking Glucophage include:
 
  • Glucophage should be taken with meals. The long-acting form, Glucophage XR, should be taken with your evening meal. Glucophage should be taken at the same time(s) each day to maintain an even level of the drug in your blood.
     
  • Do not crush or chew Glucophage XR tablets. Glucophage XR tablets must be swallowed whole.
     
  • Your healthcare provider may need to increase your dose of Glucophage. The dose of Glucophage or Glucophage XR should be increased only when necessary and should be increased slowly (by up to 500 mg every week or 850 mg every two weeks). Increasing the dose slowly usually helps to avoid side effects.
     
  • If your diabetes is not under control after one month of using the maximum Glucophage dose, talk to your healthcare provider about adding another diabetes medication.
     
  • When switching from chlorpropamide (Diabinese®) to Glucophage, special care should be taken to avoid low blood sugar (hypoglycemia). Chlorpropamide is a very long-acting medicine that may stay in your system for some time after you stop taking it.
     
  • If you do not take your Glucophage as scheduled, take your next dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue on your regular schedule. Do not take a double dose of Glucophage.
     
  • For Glucophage to work properly, you have to take it as prescribed. Glucophage will not work if you take it differently than how your healthcare provider prescribed it.
     
  • If you are unsure about anything related to Glucophage or your Glucophage dosage, please talk to your doctor, nurse, or pharmacist. Do not stop taking Glucophage without first discussing it with your healthcare provider.
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