Drug Interactions With Glucophage (Cont.)

Glucophage Interactions Explained

 
Certain Decongestants
Taking Glucophage with certain decongestants can make Glucophage less effective, increasing your chance of high blood sugar (hyperglycemia). Decongestants are in many cough and cold products, so be sure to talk to your healthcare provider before taking any cough or cold products.
 
Calcium Channel Blockers
Taking Glucophage with calcium channel blockers can make Glucophage less effective, increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your Glucophage dose, especially when starting or stopping a calcium channel blocker.
 
However, taking Glucophage with nifedipine (a calcium channel blocker) can also increase the level of Glucophage in your blood. Your healthcare provider may need to adjust your dose of Glucophage.
 
Cimetidine (Tagamet)
Taking Glucophage with cimetidine can increase the level of Glucophage in your blood, increasing your risk of side effects. Your healthcare provider may need to adjust your dose of these medications or may suggest an alternative to cimetidine.
 
Corticosteroids
Taking Glucophage with corticosteroids can make Glucophage less effective, increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your Glucophage dose, especially when starting or stopping a corticosteroid.
 
Diuretics
Taking Glucophage with diuretics can make Glucophage less effective, increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your Glucophage dose, especially when starting or stopping a diuretic.
 
Taking Glucophage with furosemide (a diuretic) can affect the levels of both furosemide and Glucophage in your blood. This may increase your risk of Glucophage side effects and may make furosemide less effective. Your healthcare provider may need to adjust your dose of these medications.
(Drug Interactions With Glucophage Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;