Precautions and Warnings With Glipizide and Metformin (Cont.)

Who Should Not Take Glipizide and Metformin?

You should not take glipizide and metformin if you:
 
  • Are allergic to Metaglip, glipizide (Glucotrol® or Glucotrol XL®), metformin hydrochloride (Fortamet®, Glucophage®, Glucophage XR®, Glumetza®, or Riomet®), or any inactive component used to make glipizide and metformin. Your healthcare provider or pharmacist has a list of the inactive ingredients.
     
  • Have kidney disease, including kidney failure (renal failure).
      
  • Have metabolic or diabetic ketoacidosis (a life-threatening condition that may occur with uncontrolled diabetes). This condition needs to be treated with insulin.
     
  • Are seriously dehydrated (have lost a lot of water from your body).
     
  • Are going to have an x-ray procedure with an injection of dyes (contrast agents).
     
  • Are going to have surgery.
     
  • Develop a serious condition, such as a heart attack, a severe infection, or a stroke.
     
  • Are 80 years old or older and you have not had your kidney function tested.
     

Precautions and Warnings With Glipizide and Metformin: A Summary

There are several situations in which glipizide and metformin should not be taken, along with a number of precautions and warnings people should be aware of before taking the drug. However, it is possible that not all precautions and warnings with glipizide and metformin were discussed in this article. Therefore, you should talk with your healthcare provider about the specific ones that may apply to you.

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;