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Glipizide and Metformin Dosing

Glipizide and Metformin Dosing for People Switching From Metformin or Glipizide

If you are switching to glipizide and metformin from either metformin or glipizide, the recommended starting dose is glipizide and metformin 2.5 mg/500 mg, taken twice daily with meals, or glipizide and metformin 5 mg/500 mg, taken twice daily with meals. The starting dose should not be higher than the dose of metformin or glipizide you were previously taking. Your healthcare provider may slowly increase your dose, if necessary, up to a total of glipizide and metformin 20 mg/2000 mg per day.

General Information on Glipizide and Metformin Dosing

Considerations for people taking glipizide and metformin include the following:
  • It is best to try to take glipizide and metformin with food in order to avoid stomach upset.
  • Glipizide and metformin should be taken at the same time(s) each day to maintain an even level of the medication in your blood.
  • If you do not take your glipizide and metformin as scheduled, take your next dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue as scheduled. Do not take a double dose of glipizide and metformin.
  • For glipizide and metformin to work properly, you have to take it as prescribed. The medication will not work if you take it differently than how your healthcare provider recommends.
  • If you are unsure about anything related to glipizide and metformin, dosing information, or anything else, talk to your doctor, nurse, or pharmacist. Do not stop taking glipizide and metformin without first discussing it with your healthcare provider.
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Glipizide and Metformin Information

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