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Glimepiride and Depression

Glimepiride and Depression: What to Look For

While depression may not be a reported side effect of glimepiride, it is extremely common in society today. In fact, in any given one-year period, 9.5 percent of the population (about 18.8 million American adults) has depression. Therefore, knowing the symptoms of depression can be helpful.
 
Possible symptoms of depression may include:
 
  • Persistent sad, anxious, or "empty" mood
  • Feelings of hopelessness and pessimism
  • Feelings of guilt, worthlessness, and helplessness
  • Loss of interest or pleasure in hobbies and activities that were once enjoyed, including sex
  • Decreased energy; fatigue; feeling "slowed down"
  • Difficulty concentrating, remembering, and making decisions
  • Insomnia, early-morning awakening, or oversleeping
  • Appetite and/or weight loss, or overeating and weight gain
  • Thoughts of death or suicide or suicide attempts
  • Restlessness and irritability
  • Persistent physical symptoms, such as headaches, digestive disorders, and chronic pain, that do not respond to treatment.
     
Keep in mind that there are other conditions that can share similar symptoms with depression.
 
(Click Symptoms of Depression to learn about the specific symptoms of depression.)
 

Glimepiride and Depression: Summary

For people taking glimepiride, depression does not appear to be a common or rare side effect. However, if you notice any possible depression symptoms while taking glimepiride -- or if something "just does not seem right," you should talk to your healthcare provider. He or she will be able to diagnose and treat the problem.
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