An Overview of Glimepiride Drug Interactions
Glimepiride ( Amaryl®) can potentially interact with many drugs. Some of the drugs that may lead to glimepiride interactions include:
- Certain antifungals, including fluconazole (Diflucan®), ketoconazole (Nizoral®), and miconazole
- Certain decongestants, such as phenylephrine (Sudafed PE®) or pseudoephedrine (Sudafed®)
- Certain seizure medications, including carbamazepine (Carbatrol®, Epitol®, Equetro®, Tegretol®), fosphenytoin (Cerebyx®), phenobarbital (Luminal®), and phenytoin (Dilantin®, Phenytek®)
- Chloramphenicol (Chloromycetin®)
- Corticosteroids, such as:
- Betamethasone (Celestone®)
- Cortisone
- Dexamethasone (Decadron®)
- Fludrocortisone (Florinef®)
- Hydrocortisone (Cortef®)
- Methylprednisolone (Depo-Medrol®, Medrol®)
- Prednisolone (Ovapred®, Pediapred®)
- Prednisone
- Triamcinolone (Kenalog®, Aristospan®)
- Disopyramide (Norpace®, Norpace® CR)
- Fluoroquinolone antibiotics, such as:
- Isoniazid
- Monoamine oxidase inhibitors (MAOIs), including:
- Niacin (nicotinic acid, Niaspan®, Niacor®, Nicolar®)
- Nonsteroidal anti-inflammatory drugs (NSAIDs), such as:
- Rifampin (Rifadin®) or rifapentine (Priftin®)
- Salicylates, such as aspirin, choline magnesium trisalicylate (Trilisate®), diflunisal (Dolobid®), and salsalate (Salflex®, Disalcid®, Amigesic®)
- Sulfonamides ("sulfa drugs"), including sulfadiazine, sulfadoxine (Fansidar®), sulfamethoxazole (Bactrim®, Septra®), and sulfisoxazole (Gantrisin®)
- Thyroid medications, such as levothyroxine (Levothroid®, Levoxyl®, Synthroid®, Unithroid®), liothyronine (Cytomel®), thyroid (Armour Thyroid®), and Thyrolar®
- Warfarin (Coumadin®, Jantoven®).
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