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Drug Interactions With Glimepiride

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Taking glimepiride with NSAIDs can increase your risk of low blood sugar (hypoglycemia). Make sure to talk with your healthcare provider before using an NSAID.
 
Oral Contraceptives
Taking glimepiride with oral contraceptives (birth control pills) can make glimepiride less effective, increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your glimepiride dose, especially when starting or stopping an oral contraceptive.
 
Phenothiazines
Taking glimepiride with phenothiazines can make glimepiride less effective, increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your glimepiride dose, especially when starting or stopping a phenothiazine.
 
Rifampin or Rifapentine
Taking glimepiride with rifampin or rifapentine can decrease the level of glimepiride in your blood, perhaps making it less effective. Your healthcare provider may need to monitor you more closely and/or adjust your dose of these medications.
 
Salicylates
Taking glimepiride with salicylates can increase your risk of low blood sugar (hypoglycemia). Make sure to talk with your healthcare provider before using a salicylate medication.
 
Sulfonamides
Taking glimepiride with sulfonamides can increase your risk of low blood sugar (hypoglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your glimepiride dose, especially when starting or stopping a sulfonamide.
 
Thyroid Medications
Taking glimepiride with thyroid medications can make glimepiride less effective, increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your glimepiride dose, especially when starting or stopping a thyroid medication.
7 Signs of High Blood Sugar

Glimepiride Drug Info

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