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Extended-Release Exenatide Side Effects

Common Side Effects

Extended-release exenatide has been studied extensively in clinical trials. In these studies, some of the people were treated with extended-release exenatide, while others were treated with other diabetes medications. In some of the studies, extended-release exenatide or the other diabetes medications were used alone; in other studies, they were used in addition to the existing diabetes medications that people were already taking. In all of the studies, the potential side effects were carefully documented and compared.
In these studies, the most common extended-release exenatide side effects included:
  • Nausea -- in up to 11 percent of people
  • Diarrhea -- up to 10.9 percent
  • Lump at the injection site -- up to 10.5 percent
  • Constipation -- up to 8.5 percent
  • Headache -- up to 8.1 percent
  • Indigestion or heartburn -- up to 7.3 percent
  • Minor cases of low blood sugar (hypoglycemia) -- up to 2 percent.
The specific percentages discussed here were taken from studies in which people were only using extended-release exenatide. Information on potential side effects from studies that combined extended-release exenatide with other diabetes medications was not included, as this data may not accurately represent true extended-release exenatide side effects.
Weight loss is a fairly predictable reaction to extended-release exenatide. In studies, people lost an average of about five pounds in 24 weeks. This weight loss is most likely due to the nausea and diarrhea that the medication often causes.

Final Thoughts

You may experience some or none of the extended-release exenatide side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
Therefore, make sure to let your healthcare provider know if you develop any side effects while using extended-release exenatide or if something "just does not seem right." While it may not be related to the medication, your healthcare provider will be able to diagnose and treat the problem.
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Extended-Release Exenatide Information

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