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Cytomel Warnings and Precautions

Before starting thyroid replacement therapy with Cytomel, warnings and precautions for the drug should be discussed with your healthcare provider to help minimize risks. You should tell your healthcare provider if you have diabetes, heart problems, or any allergies before using the medication. Warnings and precautions with Cytomel also apply to people untreated adrenal insufficiency or untreated hyperthyroidism.

What Should I Tell My Healthcare Provider Before Taking Cytomel?

You should talk with your healthcare provider prior to taking Cytomel® (liothyronine sodium) if you have:
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings With Cytomel

Warnings and precautions to be aware of prior to taking Cytomel include the following:
  • People who do not have thyroid problems should never use Cytomel to lose weight. A Cytomel dosage high enough to cause weight loss in such people is often high enough to cause serious or even life-threatening problems.
  • Thyroid hormone medications (including Cytomel) should not be used to treat infertility in people who do not have thyroid problems, as they are not effective for such use.
  • The medication can make heart problems worse. If you have heart problems, your healthcare provider should start you at a low dosage and slowly increase it. If you notice that Cytomel makes your heart symptoms worse, let your healthcare provider know right away.
  • If you have diabetes, it is a good idea to check your blood sugar more often when starting or stopping Cytomel (or when changing your dose), as the medication can affect your blood sugar.
  • Cytomel can potentially interact with many other medications (see Cytomel Interactions).
  • Cytomel is considered a pregnancy Category A medication. This means that it is safe for use during pregnancy (see Cytomel and Pregnancy).
  • Cytomel does pass through breast milk in humans, although it is not likely to cause problems. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Cytomel and Breastfeeding).
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