Cytomel Interactions

More Information on Interactions With Cytomel

The following sections explain in detail the potentially negative interactions that can occur when Cytomel is combined with any of the drugs listed above.
 
Bile Acid Sequestrants
Bile acid sequestrants can bind to Cytomel in the digestive tract, preventing it from being absorbed into the body. Make sure to separate your Cytomel dosage from a bile acid sequestrant by at least four to five hours.
 
Calcium
Calcium can bind to Cytomel in the digestive tract, preventing it from being absorbed into the body. This interaction was discovered with a different thyroid medication, but it is thought that it probably occurs with Cytomel as well. Make sure to separate Cytomel and calcium by at least four hours.
 
Certain Seizure Medications
Taking Cytomel with some seizure medications may change the amount of Cytomel your body needs, and your healthcare provider may need to adjust your dosage as a result.
 
Diabetes Medications
When you first start Cytomel (or increase your dose), your healthcare provider may need to increase the dose of your diabetes medications. Check with your healthcare provider before taking Cytomel if you are already taking diabetes medications.
 
Digoxin
Cytomel can make digoxin less effective and may increase its potentially toxic effects, which can be dangerous. Check with your healthcare provider, as your digoxin dosage may need to be increased.
 
Estrogens
Estrogens can lower the level of Cytomel in your blood, perhaps making it less effective. Your healthcare provider may need to adjust your dose of Cytomel if you start or stop taking an estrogen medication.
(Cytomel Interactions Continued: Page 3)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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