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Cushing's Syndrome

Diagnosing Cushing's Syndrome

In order to make a Cushing's syndrome diagnosis, the doctor will ask a number of questions concerning subjects such as:
  • The person's medical history
  • His or her current symptoms
  • Whether there is a family history of any medical problems
  • What medicines the person is taking.
The doctor will also perform a physical exam, looking for any signs of the disease. If these suggest Cushing's syndrome, more tests are done.
Testing for Cushing's syndrome typically involves a two-step process. First, doctors order a test to see if there is too much cortisol in the body. This test is called a 24-hour urinary free cortisol level, and it measures how much cortisol is being produced.
If Cushing's syndrome is present based on the urine test, then doctors order further tests to determine the cause.
These tests may include:
  • Dexamethasone suppression test
  • CRH stimulation test
  • Dexamethasone-CRH test
  • Petrosal sinus sampling
  • Imaging tests.
(Click Cushing's Syndrome Testing for more information.)

Treating Cushing's Syndrome

Treatment for Cushing's syndrome depends on the specific reason for excess cortisol. Some options for treatment include:
  • Surgery
  • Radiation
  • Chemotherapy
  • Cortisol-inhibiting medicines
  • A combination of these treatments.
(Click Cushing's Syndrome Treatment for more information.)
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Cushing's Syndrome Information

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