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Symptoms of Cushing's Disease

For children and teenagers with Cushing's disease, symptoms may include extreme weight gain, missed periods in girls, and high blood pressure. Symptoms in adults may include such things as excess hair growth, skin problems, and muscle weakness. Other signs and symptoms seen in adults can include diabetes, sleep disturbances, and osteoporosis.

Signs and Symptoms of Cushing's Disease

When an ACTH-secreting pituitary tumor produces too much cortisol in the body, symptoms of Cushing's disease can result. These symptoms will vary among patients. The symptoms of this disease also vary based on the person's age.

Symptoms in Children and Teenagers

Children and teenagers with Cushing's disease can have the following symptoms:
  • Extreme weight gain, especially around the midsection and upper back
  • Reddish-blue streaks on the skin
  • Excess hair growth
  • Growth retardation
  • Missed periods in teenage girls
  • High blood pressure
  • Acne
  • Tiredness and weakness
  • Either very early or late puberty.

Symptoms in Adults

Adults with Cushing's disease may also have symptoms such as:
  • Extreme weight gain, especially around the midsection and upper back
  • High blood pressure
  • Skin problems
  • Excess hair growth.
Additional symptoms of Cushing's disease in adults may include:
  • Muscle weakness
  • Purplish-pink stretch marks on the abdomen, thighs, buttocks, arms, and breasts
  • Moodiness, irritability, or depression
  • Sleep disturbances
  • Diabetes
  • Menstrual disorders in women
  • Osteoporosis
  • Decreased fertility in men
  • Diminished or absent desire for sex.
7 Signs of High Blood Sugar

What Is Cushing's Disease?

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