Cushing's disease is a hormonal disorder caused by a non-cancerous pituitary tumor that produces large amounts of adrenocorticotropin (ACTH) for an extended period. The excess ACTH causes the body to produce extra cortisol. Symptoms of Cushing's disease can include excess hair growth, high blood pressure, skin problems, and acne. The disease occurs five times more often in women than in men. In making a Cushing's disease diagnosis, a healthcare provider usually asks about a patient's medical history, current symptoms, and whether there is a family history of any medical problems, among other things. Treatment options for Cushing's disease may include surgery, radiation therapy, and drug therapy.