Precautions and Warnings With Alogliptin and Pioglitazone
Although it is an effective diabetes drug, alogliptin and pioglitazone may not be safe for people who are taking certain medications or for women who are pregnant or nursing. Other precautions for using alogliptin and pioglitazone safely include warnings for people who have liver disease, weak bones, or heart problems. You can minimize risks for these complications by reviewing these precautions with your healthcare provider.
You should talk with your healthcare provider prior to taking alogliptin and pioglitazone (Oseni®) if you have:
- Liver disease, such as hepatitis, cirrhosis, or liver failure
- Kidney disease, such as kidney failure (renal failure)
- Had pancreatitis (inflammation of the pancreas)
- Gallstones (stones in your gallbladder)
- Congestive heart failure or other heart problems
- Swelling due to fluid retention (edema)
- Weak or thin bones, such as osteoporosis, osteopenia, or if you have broken a bone in the past
- Cancer of the bladder or a history of it
- An eye condition known as macular edema (swelling or thickening of the macula, an area in the back of the eye)
- Plans for a surgery
- A history of alcoholism or drink alcohol frequently
- Not gone through menopause and have irregular periods
- Any allergies, including to foods, dyes, or preservatives.
In addition, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.