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Precautions and Warnings With Alogliptin and Metformin

If you have liver or kidney disease, you may not be able to use alogliptin and metformin. Warnings and precautions also apply to people who will be undergoing surgery or a medical procedure that uses contrast dye, as well as women who are pregnant or breastfeeding. To help minimize complications, talk to your healthcare provider about your medical history and all medications or supplements you are taking.


What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking alogliptin and metformin (Kazano®) if you have:
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • Kidney disease, such as kidney failure (renal failure)
  • Had pancreatitis (inflammation of the pancreas)
  • Gallstones 
  • Congestive heart failure (CHF) or other heart problems
  • Plans for a surgery or medical procedure, including x-rays or procedures where you will be given an injection of dye or contrast agent
  • A condition called metabolic acidosis or have had diabetic ketoacidosis (increased ketones in your blood or urine)
  • Low vitamin B12 levels (pernicious anemia)
  • A history of alcoholism or drink alcohol often
  • Any allergies, including to foods, dyes, or preservatives.
In addition, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
Diabetes Tips for Seniors

Alogliptin and Metformin Information

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