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Alogliptin and Metformin Side Effects

In clinical studies on alogliptin and metformin, common reactions included diarrhea, back pain, and signs of the common cold. Fortunately, adverse reactions, if any, are usually mild and easily treated. Potentially serious alogliptin and metformin side effects that require medical care include signs of liver damage, low blood sugar levels, and pancreatitis.


An Introduction to Side Effects of Alogliptin and Metformin

As with any medicine, alogliptin and metformin (Kazano®) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with alogliptin and metformin. Your healthcare provider can discuss a more complete list with you.)

Serious Alogliptin and Metformin Side Effects

Some side effects of alogliptin and metformin are potentially serious and should be reported to your healthcare provider right away. These include but are not limited to:
  • Signs of a rare but serious condition known as lactic acidosis, which include:
    • Extreme weakness, tiredness, or sleepiness
    • Unusual muscle pain
    • Unexplained nausea, vomiting, or diarrhea
    • Feelings of coldness, especially in the arms and legs
    • Dizziness or lightheadedness
    • A slow or irregular heartbeat
  • Signs of pancreatitis (inflammation of the pancreas), such as:
    • Abdominal (stomach) pain or tenderness that may radiate to the back
    • Nausea
    • Vomiting
  • Signs of low blood sugar (hypoglycemia), such as:
    • Shakiness
    • Sweating
    • Hunger
    • Headache
    • Dizziness
    • Confusion
    • Blurry vision
    • Change in mood, such as irritability
    • A fast heartbeat
  • Signs of liver problems, such as:
    • Abdominal (stomach) pain or swelling
    • Loss of appetite
    • Unexplained fatigue
    • Dark urine
    • Yellowing of the skin or whites of the eyes
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching, flaking, or peeling of the skin
    • Unexplained swelling, especially of the face, lips, or throat
    • Difficulty swallowing or breathing.
Common Symptoms of Diabetic Neuropathy

Alogliptin and Metformin Information

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