Alogliptin and Metformin
You should talk with your healthcare provider prior to taking this medication if you have:
- Liver disease, such as hepatitis, cirrhosis, or liver failure
- Kidney disease, such as kidney failure (renal failure)
- Had pancreatitis (inflammation of the pancreas)
- Congestive heart failure (CHF) or other heart problems
- Plans for a surgery or medical procedure, including x-rays or procedures where you will be given an injection of dye or contrast agent
- A condition called metabolic acidosis or have had diabetic ketoacidosis
- Low vitamin B12 levels (pernicious anemia)
- A history of alcoholism or drink alcohol often
- Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant (see Kazano and Pregnancy)
- Breastfeeding (see Kazano and Breastfeeding).
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Alogliptin and Metformin to learn more, including information on who should not take the drug.)
Although alogliptin and metformin itself has not been studied in clinical trials, the combination of the two active ingredients in the drug has been. In these studies, people who had type 2 diabetes that was not already well controlled with diet, exercise, or certain other medications had a reduction in their hemoglobin A1c (HbA1c) and fasting blood glucose when given the combination.