Addison's disease is a medical condition that occurs as a result of the destruction of the adrenal cortex. The cells in the adrenal cortex produce hormones that are responsible for certain bodily functions, such as: slowing the immune system's inflammatory response, maintaining blood pressure, and regulating the metabolism of proteins, carbohydrates, and fats.

 

Addison's disease is generally characterized by weight loss, muscle weakness, chronic fatigue, low blood pressure, and sometimes darkening of the skin in both exposed and non-exposed parts of the body.

 

Although Addison's disease is not curable, treatment (usually involving medication) can help control the condition. Treatment for Addison's disease involves replacing, or substituting, the hormones that the adrenal glands are not making.