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Actoplus Met XR Warnings and Precautions

If you are taking Actoplus Met XR for type 2 diabetes and have an upcoming surgery planned, you will need to stop taking this medicine temporarily until you are eating normally again. Other warnings and precautions with Actoplus Met XR apply to women who are pregnant or breastfeeding, people with certain allergies, and people with serious heart or kidney conditions.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Actoplus Met® XR (pioglitazone and metformin XR) if you have:
  • Low vitamin B12 levels (pernicious anemia)
  • Kidney problems, including kidney failure (renal failure)
  • An upcoming surgery or procedure, including x-rays and other radiology procedures
  • Heart problems of any kind, especially congestive heart failure (CHF)
  • A history of heart attack or stroke
  • Liver problems, including liver failure or cirrhosis
  • Any allergies, including to food, dyes, or preservatives.
Also, let your healthcare provider know if you:
  • Are pregnant or thinking of becoming pregnant
  • Are breastfeeding
  • Are having problems getting pregnant
  • Are premenopausal without regular menstrual periods
  • Drink alcohol.
In addition, tell your healthcare provider about all other medicines you may be taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
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Actoplus Met XR Medication Information

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