Actoplus Met XR Uses
The U.S. Food and Drug Administration has approved Actoplus Met XR for the treatment of type 2 diabetes in adults. It cannot be used to treat type 1 diabetes, nor can children use it. Actoplus Met XR works by improving insulin sensitivity and decreasing the amount of sugar produced by the liver. Occasionally, it may be prescribed off-label to treat polycystic ovarian syndrome.
What Is Actoplus Met XR Used For?Actoplus Met® XR (pioglitazone and metformin XR) is a prescription medication that is used to treat type 2 diabetes. The drug contains a combination of different diabetes medications: pioglitazone hydrochloride (Actos®) and extended-release metformin hydrochloride. These two drugs work in different ways to help lower blood sugar.
Actoplus Met XR is a long-acting medication that is taken just once a day, in the evening. It cannot be used to treat type 1 diabetes.
Using Actoplus Met XR for Type 2 Diabetes
Type 2 diabetes is the most common type of diabetes (see Diabetes Types). It is also sometimes called adult-onset diabetes and noninsulin-dependent diabetes. Type 2 diabetes is a condition involving insulin resistance.
With insulin resistance, cells in the body do not respond to insulin as well as they normally should. As a result, the cells do not take sugar out of the blood very well. This is why people with type 2 diabetes have high blood sugar.
Over time, high blood sugar can lead to a number of problems, including:
(Click Diabetes Complications for more information.)
The cause of type 2 diabetes is not fully understood, although it is known that obesity and genetics play important roles. If blood sugar cannot be lowered enough through lifestyle changes (such as weight loss, diet, and exercise), a medication for type 2 diabetes, such as Actoplus Met XR, may be prescribed.