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Actoplus Met XR Uses

Why Is Actoplus Met XR Used as Part of Diabetes Treatment?

The main goal of any diabetes treatment plan is to lower your blood sugar levels (as measured by your hemoglobin A1c [HbA1c]) enough to reduce your risk for developing problems related to the condition (see Diabetes Complications).
Some diabetes drugs force the pancreas to produce more insulin (see Actoplus Met XR Alternatives). These medications are effective, but can cause dangerously low blood sugar (hypoglycemia). Because Actoplus Met XR does not force the pancreas to make more insulin, the risk of dangerously low blood sugar with this medicine is low.
In some people, Actoplus Met XR may need to be taken with other diabetes medicines. For example, if type 2 diabetes is untreated for a long time, the pancreas may not be able to make insulin anymore. In these people, using Actoplus Met XR alone will not be effective, since the effects of the drug depend on the presence of insulin in the body. These people will need to take insulin along with Actoplus Met XR.
For more information about controlling diabetes through lifestyle choices, click any of the following eMedTV links:

How Does This Medicine Work?

The two medications in Actoplus Met XR work differently and have different effects in the body:
  • Pioglitazone is part of a group of diabetes medicines called thiazolidinediones (or sometimes called "glitazones"). Pioglitazone helps to improve insulin sensitivity. This means that pioglitazone helps your body respond to its natural insulin better, which helps to lower blood sugar.
  • Metformin works in several ways. It decreases the amount of sugar (glucose) made by the liver. Metformin can also decrease the amount of sugar absorbed into the body from the diet and can make insulin receptors more sensitive, helping the body respond to its own insulin better. All of these effects cause a decrease in blood sugar levels.
7 Signs of High Blood Sugar

Actoplus Met XR Medication Information

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