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Actoplus Met XR Drug Interactions

Because Actoplus Met XR can interact with several drugs, it is important to tell your healthcare provider about all other medications you are taking. If Actoplus Met XR is taken with atorvastatin, seizure medications, or diuretics, for example, the medicines may be less effective or you may be at an increased risk for side effects.

An Overview of Interactions With Actoplus Met

Actoplus Met® XR (pioglitazone and metformin XR) can potentially react with several different medicines. Some of the drugs that can lead to interactions with Actoplus Met XR include:
  • Cimetidine (Tagamet®)
  • Corticosteroids, such as:
    • Betamethasone (Celestone®)
    • Cortisone
    • Dexamethasone (Decadron®)
    • Fludrocortisone (Florinef®)
    • Hydrocortisone (Cortef®)
    • Methylprednisolone (Depo-Medrol®, Medrol®)
    • Prednisolone (Orapred®, Pediapred®)
    • Prednisone
    • Triamcinolone (Kenalog®, Aristospan®)
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Actoplus Met XR Medication Information

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