Actoplus Met XR and Breastfeeding
Although one of the active ingredients in Actoplus Met XR (pioglitazone and metformin XR) has been studied in breastfeeding women, the other active ingredient has not. Therefore, the problems this drug might cause are unknown. Your healthcare provider will make a recommendation based on your particular situation. If you do take Actoplus Met XR, your infant's blood sugar may require monitoring.
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At this time, it is unknown if Actoplus Met XR® (pioglitazone and metformin XR) is safe for use in nursing women. Therefore, if you are breastfeeding a child, you should talk with your healthcare provider about taking Actoplus Met XR.
No research has been done to see if the pioglitazone component of Actoplus Met XR passes through breast milk in humans, although studies have shown that the drug passes through breast milk in rats.
The metformin component does pass through breast milk, although in low amounts. Studies suggest that metformin use in the mother is unlikely to cause problems in the nursing baby. However, the possibility of rare problems cannot yet be ruled out.
If a woman decides to take Actoplus Met XR while breastfeeding, it would be a good idea for the baby's blood sugar to be monitored to make sure that it is not dropping too low.
You should discuss breastfeeding and Actoplus Met XR with your healthcare provider. Each woman's situation is different, and you and your healthcare provider understand your situation best. After considering what you want and expect, as well as your current health situation, the two of you can make a shared decision that is right for you.