Drug Interactions With Acarbose

There are a number of potential drug interactions with acarbose. For example, acarbose can interact with certain medicines -- including sulfonylureas and insulin -- to increase your risk of low blood sugar. Also, taking acarbose along with niacin, isoniazid, or estrogens (among other drugs) can make acarbose less effective, increasing your risk of high blood sugar. Some other drugs that can potentially interact with acarbose include calcium channel blockers, digestive enzyme replacements, and phenothiazine medications.

 

Drug Interactions With Acarbose: An Overview

Acarbose (Precose®) can potentially interact with a number of other medicines. Some of the medicines that may lead to acarbose interactions include:
 

 

 

  • Certain decongestants, such as phenylephrine (Sudafed PE®) or psuedoephedrine (Sudafed®)
     
  • Corticosteroids, such as:

 

    • Betamethasone (Celestone®)
    • Cortisone
    • Dexamethasone (Decadron®)
    • Fludrocortisone (Florinef®)
    • Hydrocortisone (Cortef®)
    • Methylprednisolone (Depo-Medrol®, Medrol®)
    • Prednisolone (Ovapred®, Pediapred®)
    • Prednisone
    • Triamcinolone (Kenalog®, Aristospan®)

 

  • Digestive enzyme replacements, such as amylase, pancreatin, and pancrelipase
     
  • Diuretics, such as:

 

 

 

 

 

 

(Drug Interactions With Acarbose Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;