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Drug Interactions With Acarbose

Estrogens
Taking acarbose with estrogens can make acarbose less effective, increasing your chance of high blood sugar (hyperglycemia). If you are taking acarbose with an estrogen, you may need to be monitored more closely, and your healthcare provider may need to adjust your acarbose dose -- especially when you are starting or stopping an estrogen.
 
Insulin
Acarbose is approved for use with insulin. However, taking acarbose while using insulin can increase your risk of low blood sugar (hypoglycemia). If you have low blood sugar, your healthcare provider may need to decrease your dose of these medications.
 
Isoniazid
Taking acarbose with isoniazid can make acarbose less effective, increasing your chance of high blood sugar (hyperglycemia). If you are taking acarbose with isoniazid, you may need to be monitored more closely, and your healthcare provider may need to adjust your acarbose dose -- especially when you are starting or stopping isoniazid.
 
Niacin (Nicotinic Acid, Niaspan, Niacor, Nicolar)
Taking acarbose with niacin can make acarbose less effective, increasing your chance of high blood sugar (hyperglycemia). If you are taking acarbose with niacin, you may need to be monitored more closely, and your healthcare provider may need to adjust your acarbose dose -- especially when you are starting or stopping niacin.
 
Oral Contraceptives
Taking acarbose with oral contraceptives (birth control pills) can make acarbose less effective, increasing your chance of high blood sugar (hyperglycemia). If you are taking acarbose with a birth control pill, you may need to be monitored more closely, and your healthcare provider may need to adjust your acarbose dose -- especially when you are starting or stopping a birth control pill.
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